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THE INESCAPABLE LOGIC OF ANY VALID ADDICTION ETIOLOGICAL PARADIGM


WHAT OTHER DISEASE....?


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AIMING AT AN UNDERSTANDING OF ADDICTIONS


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WHY WE DON'T NEED HYPOISM.


Why We Need Hypoism: A Comparison of the Principles and Consequences between the two Paradigms


Entitled to Your Opinion? Not Anymore.


HYPOICMAN: A non-recovering, unimpressed Hypoic


The Field of Addictionology: A Golfing Analogy


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The Addiction Treatment Fraud Finally Exposed


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Third Millennium N4A Conference Keynote Address on Hypoism - Pathophysiology in Addictions vs. Superstition


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Gateway theory finally disproven


Celera Discovers Millions of Tiny Genetic Differences in People

Interesting Addiction Science



Clinically Important Neurotransmitter Deficiencies

Hypoism Magazine-Articles by and for Hypoics



EMBRYONIC HYPOISM CIRCA 1968


#1 Hatred, #2 The Words: Opinion, Belief, and Knowledge, #3 Hate Addiction


#4 The Drug War War, #5 Evolution vs. Creationism Revisited for Addictions


#6 American Society for Addiction Medicine Statement for Recovering Physicians


#7 Issues Peculiar to the Disease of Addictions


#8 Critique of Alan Lechner's (NIH), "The Hijacked Brain Hypothesis."


#8a. Update!! Dr. Leshner recently makes a change


#9 MY STORY - The Doctor Drug War - Wrong and Wasteful p.1, 1/6/00


The Doctor Drug War p.2


Doctor Drug War p.3


Doctor Drug War p.4


Doctor Drug War p.5


Affidavit for judicial review of NYS Dept. of Ed.


#10 The Superstition Instinct 3/1/00


#11-Conflict of Interest in Addiction Research


#12 - Controlled Drinking Lands On Its Ass


#13 - The Kennedy Curse or Kennedy Hypoism?


#14 - The Lord's Prayer for Hypoics


#15 - Replacing Alan Leshner is the only way to end the Drug War


#16 - The Brain Addiction Mechanism and the COGA Study


#17 - Letter to the director of the National Academy of Medicine's Board on Neurobiology and Behavior Health on Addictions


#18 - Is Addiction Voluntary, A Choice, as Leshner and NIDA Insist?


#19 - Bush's Alcoholism and Lies


#20 - A P/R Paradigm Addict - "Cured?"


#21 - Congress Misled and Lied to by NIAAA


#22 - Special Letter to the Times on Addiction Genetics


#23 - JAMA Editor Publishes According to His Beliefs, Not Science


#24 - Smoking as Gateway Drug. I Don't Think So!


#24B - IS COCAINE ADDICTION CAUSED BY COCAINE?


#25 - One Less Heroin Addict. But At What Cost?


#26 - An Open Letter to the Judge who Sentences Robert Downey, Jr.


#27 - Letter To Schools About The Pride Program Against Drugs


#28 - A Letter To Bill Moyers, Close To Home, and PBS


#29 - HYPOISM IS ACTUALLY A DISEASE OF THE "WILL"


#30 - Brookhaven Labs Provide More Evidence For Hypoism


#31 - Addiction Prevention Revisited


#32 - DRUG WAR EVALUATION BY THE NATIONAL ACADEMY OF SCIENCE


#33 - NIDA Is Close But No Cigar


#34 - Bush's Addict Discrimination and Hypocricy Begins


#35 - Maya Angelou's, "Still I Rise."


#36 - Leshner Lies To Congress


#37 - Addiction Combos


#38 Brain tumor proves Hypoism hypothesis


#39: So-called Availability Debunked as Contributor of Addictions


#40 - Hypoism Reproduced By A Pill


PIMMPAL Complex


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The Hypoism Blog - The Addiction Blog



The Addiction Blog 4/17/11 -


The Addiction Blog 9/14/10 - 4/16/11


The Addiction Blog 11/12/09 - 9/14/10


The Addiction Blog 7/23/09 - 11/09/09


The Addiction Blog 5/16/09 - 7/22/09


The Addiction Blog 3/3/09 - 5/13/09


The Addiction Blog 8/3/08 - 3/3/09


The Addiction Blog 4/1/07 - 8/3/08

old letters



My NY Times Letters to the Editor page 1.


My NY Times Letters to the Editor page 2.


My NY Times Letters to the Editor page 3.


My NY Times Letters to the Editor page 4.


My NY Times Letters to the Editor page 5.


My New York Times Letters to the Editor page 6.


My Letters to the editor of the NY Times page 7.


My Letters to the Editor of the NY Times page 8.


NY Times Letters Page 9.


New York Times Letters Page 10


My NYT Letters page 11


NY Times Letters page 12.


NY Times letters p. 13


Letters to the NY Times page 14.


Letters to Newsday


Letters To The Los Angeles Times


Creationism/Evolution Letter to BAM 11-25-05

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The Future of Addictions

Addict Discrimination in the News



Mandated Treatment for Welfare Recipients


Anorectic Murdered by Doctors out of Ignorance and "Desperation"(10/20/99)


Six Dead Heroin Addicts-Enough? 10/31/99


American Society of Addiction Medicine Discrimination


Darryl Strawberry Punished Again


South Carolina Forces Pregnant Women to Take Drug Tests


When it comes to drugs, the constitution doesn't apply


Parents of Overweight Girl Will Sue New Mexico


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Hypoics are born, not made.

Hypoism  
Dan F. Umanoff, M.D.  
941-926-5209  
8779 Misty Creek Dr.  
Sarasota, Florida 34241  

dan.umanoff.md@gmail.com  




10/23/00
The letters speaking to America's Endless War on Fat all show the same denial of the science, denial of the genetics, denial of the neurobiology, and a misunderstanding of how the genetics and neurobiology work in a human. Refer back to How the Body Knows When to Gain or Lose, from 10/17, where Dr. Flier uses the words control, conscious, will power, and free will to characterize what certain obese peoples' eating behaviors are not about. Several quotes from the letters show the conceptual problem the current paradigm has with obesity. "I'm all for discipline, but being better informed about the way our bodies work is the first step to weight control." True, but with the emphasis on how the brain works to produce behaviors. "Doctors who care about health know there are better ways to achieve and maintain a healthy weight than learning to think about food as the enemy." True, the underlying brain physiology, not the symptom, eating. Then the psychiatrist queries, "Why must feeling trim and healthy, unencumbered by the fatigue of a diet laced in fat, be viewed as loss?" This question pathetically comes from a doctor who is actually "treating" obese patients. Doctor, it isn't viewed as a loss, the unconscious brain neurobiology defines it as a loss. The tail wags the dog, doctor. It's not a view, it's a disease outside their control. The only realistic way for people to deal with the compulsive use of neurobiologically mediated instincts and instinct system mediated behaviors (addictions) such as eating, sex, drugs, gambling, etc. is through acknowledgment (I don't have control and never will), realization (My attempts to control have lead to continued failure to control and misery), surrender (I give up the control), and acceptance (I will let someone else, my decision consultant, another recovering person voluntarily selected by the addict and unpaid, control my behavior on this issue). This sequence is exactly the opposite of what the "experts" are trying to "teach" addicts, and is based on the neurobiology rather than on a faulty belief system. Of course, this is why addicts are overwhelmingly failing to control their addictions - bad for the addict, but good for the therapist's pocketbook. Addiction therapists (and our society at large) have a conceptual bias concerning how the brain works to produce behaviors in addicts. I call this the psychological/religious paradigm (the religion of psychology). There never has been any proof for this paradigm, yet it is still believed to the detriment of addicts around the world. I have attempted to shift this paradigm over to Hypoism, one that fits with Dr. Flier's view of obese people and addicts in general, the only realistic one if you honestly and openmindedly look at addictions. Either Hypoism is correct or there are a lot of stupid and obstreperous addicts out there. Wake up New York Times so your readers can discover the neurobiological and recovery reality of Hypoism where the emphasis is on how the brain works rather than on the addictors and the conscious origins of specific addictions. I know it blows your belief system, but for the sake of addicts, let it go, at least in this instance. It's killing and maiming too many good people.
10/24/00
Erica Goode states in, Watching Volunteers Eat, Psychiatrists Seek Clues to Obesity, "They have uncovered abnormalities in the biological systems controlling hunger and satiety that may play a role in many eating disturbances. And they have learned that eating disorders tend to run in families, suggesting that the vulnerability to such problems may be at least in part genetic." This statement is a typically biased Erica Goode remark minimizing genetics and biology. Eating disorders are rather genetic disorders with some environmental influences, not the opposite. [See: Br J Psychiatry 1998 Jul;173:75-9 Genetic epidemiology of binging and vomiting. Sullivan PF, Bulik CM, Kendler KS Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond. Conclusion: In contrast to 'environmentalist' theories, our results suggest that genetic influences may be of particular relevance to the aetiology of binging and vomiting.] Other genetic addiction studies by them and others show the same thing. They are profoundly genetic based. http://www.nvo.com/hypoism/recentgeneticstudiesonvariousaddictionsfromalargetwinregistr/ The history of addictions, eating disorders being one of them, has traversed a landscape of superstition based etiologies over the last 100 years or more. They can all be called environmentalist, based on psychobabble mythologies mixed with conscious choice and willful decisions. These theories have killed and maimed uncounted millions of addicts and their families. New York Times science writers subscribe to this paradigm. However, if one reviews the history of this field you will find one dead environmentalist theory after another littering the battle field along with countless dead addicts killed by these biased theories. This reality is paralleled in the overall field of Psychiatry. Environmentalism has been replaced by biology (frequently genetic based) in one instance after another such as personality types (temperaments), Tay-Sachs, autism, schizophrenia, epilepsy, Huntington's disease, Parkinson's, Alzheimer's, alcoholism, depression, neuroticism, and many many others. Even happiness has been shown to be genetically based and innate (Lykkens). Yet, psychiatry and the Times persists in minimizing genetics and biology for the sake of environmentalism and its various superstition based "therapies" at the expense of the sufferers. I couldn't help but laugh at the picture of psychiatrists watching fat people eating as a way to understanding fatness. Only a psychiatrist would do something as ridiculous. I can see them in bars watching alcoholics drinking too! This approach has resulted in no real improvements in understanding addictions. If real physicians and scientists were enlisted to understand these behaviors instead of environmentally biased psychiatrists working within a prejudiced and dead environmentalist paradigm we would have real answers to these disorders in a heart beat. All the information about the etiology of addictions, compulsions, and other biology based "behavioral" diseases is readily available to make the complete transition from superstition and bias to neurobiology if only the field were open to use it. Biased psychiatrists will not even look at it. My book on the neurobiology of addictions does just this but has been ignored by biased psychiatrists and newspapers alike. Massive damage to people with these disorders as well as to our society in general will persist as long as long as this continues. Shame on the Times for not exploring and reporting on my book as a means of helping addicts.
10/28/00
For the first time in the history of the NY Times science section we see a glimpse of reality concerning human "behavioral" problems. "Experts are coming round to the view that the body has a preset range; gluttony can take you up to the upper limit, rigorous diet can put you at the bottom limit. But almost nothing can take you outside those limits. Though food intake seems to be under conscious control, it may in fact be controlled beyond the will's limit or the mind's knowledge just as are temperature or salt balance." The key word of this quote is SEEMS. I've been writing you letters concerning this misperception surrounding conscious control of other instincts and the use of their regulating neurotransmitter substitutes (mood-altering drugs) for 7 years and finally Nick Wade makes the statement himself. My Hypoism paradigm which concerns addictions to instincts such as eating, sex, gambling, and drugs states this categorically and has been ignored for all this time. The above quote needs to be extended to all instincts and drugs in certain people who genetically don't have conscious control over their use in the nonrecovering state. These are hypoics as defined in my book, Hypoic's Handbook. Maybe Nicholas Wade would read this book and report to your readers on a general paradigm concerning these issues; a paradigm that explains the SEEMING "conscious stupidity" of all addicts, not just fat people. What SEEMS under conscious control in nonhypoics is never under conscious control in hypoics. This is the key to understanding all people who misuse drugs and instincts. Hey, check out my book. It's been waiting impatiently for you Nick. It's all there, and what these people can do about it too.
10/31/00
Supreme Court Accepts Case That Challenges Prison Law, NYT 10/31/00, raises important issues on administrative law in this country that requires complainants to exhaust local or state administrative remedies before using any real legal remedies. Administrative law has none of the civil rights safeguards found in real courts and cases may be dragged on for years before these remedies are exhausted. This process is usually futile and very costly, as it has been in my medical license revocation case. One might run out of money for lawyers before getting to a real court where civil rights laws might be used against administrative perpetrators. Of course, this is why administrative law exists, to prevent access to any real legal remedies. Thus, I have started The National Association for the Advancement and Advocacy of Addicts (N4A). Our main purpose, besides reviewing addiction research for scientific validity and disseminating valid information about addictions and recovery, is to legally advocate free of charge for discriminated and abused addicts in any area; in administrative, civil, or criminal courts. The N4A is the only legal advocacy group for addicts and by addicts with no ulterior motives or conflicts of interest.
11/5/00
I laughed and cried as I read the article, Citing Intolerance, Obese People Take Steps to Press Cause, NYT 11/5/00. I was also angry; angry at both sides of the issue. Not only do "normal" people misunderstand fat people, they misunderstand all Hypoism manifestations. Moreover, hypoics themselves misunderstand their own symptoms. All this misunderstanding is due to scientific ignorance and associated denial of biology, including the biology of instinctive xenophobia, the basis for discrimination and prejudice. People with many hypoism symptoms such as massive obesity, alcoholism, and ADD have formed groups to stop their discrimination but are unwilling to base these groups on a premise that both informs people about the true biology of their symptom as well as transforming public attitudes based on this emotionally neutral biology as in previously discriminated medical diseases such as epilepsy, down's syndrome, and autism not to mention depression and schizophrenia, etc. As stigmatized medical diseases are better understood scientifically, the stigma and discrimination recedes. This is not happening in hypoism for two reasons: 1) the science is wrong and confused and frequently based on biased science, and 2) the people with the disease, in this case fat people, don't want to see their problem as based on a true disease - it makes them feel defective and they don't want to feel this way. Well, the only way to overcome both the symptoms (addictions) and the discrimination is to do exactly what addiction scientists and addicts don't want to do - accept the biology and base recovery on that biology. I have done this for all addictions. The biology is called Hypoism. The group that fights discrimination of all addicts, The National Association for the Advancement and Advocacy of Addicts (N4A), is based on this biological premise. Hypoism puts all this together in one complete package yet is ignored because the biased scientists don't like it and the addicts don't like it. Obviously, the Times doesn't like it either because I've been informing it about Hypoism for 7 years and it hasn't examined it nor published a single letter to the editor about it. Until Hypoism is seen as the cause for these assorted addictions, leading to massive societal understanding and acceptance, discrimination and nonrecovery from addictions along with their associated medical and social problems will be perpetuated. I invite all groups formed around individual addictions to learn about Hypoism and to coalesce into the N4A to form one large and powerful organization to effectively deal with all their issues. I also invite the Times to explore the Hypoism hypothesis.
11/9/00
The letter below clearly shows the height of NIDA'a arrogance and stupidity and is an example of the crap coming out of addiction pseudoresearch and the addiction research conspiracy mentioned on my article at: http://www.nvo.com/hypoism/15replacingalanleshneristheonlywaytoendthedrugwar/ Where is the peer review? This study is so pathetic it also speaks to the complete irresponsibility of JAMA, the so-called medical journal that publishes whatever Leshner wants it to. The lack of integrity involved speaks for itself. It also exemplifies the crap the NY times will publicize while completely ignoring Hypoism. Someone other than me needs to hold all their feet to the fire, but no one else realizes what crap it is. Most people and addictionologists will buy this nonsense and probably cite is as another example of good research funded by NIDA and produced by its funding.

Anxiety Seen in Teenagers Who Smoke, NYT 11/8/00, does not show what the authors say it shows and is scientifically invalid and misleading. This study only shows that the presmoking psychological testing didn't differentiate the ones who would go on to the latter symptoms. The only way to say that smoking causes these anxiety symptoms is to take two matched groups, make one group smoke and the other not, and see if there is a difference in anxiety symptoms down the road. This study is much like the ones purported to show that marijuana is a "gateway drug" to cocaine or other "hard" drugs. It is also reminiscent of George Valliant's "The Natural History of Alcoholism" study that did psychological testing on a group of Bostonians and couldn't differentiate from these tests which would go on to alcoholism in the future. The same kind of incorrect conclusion was drawn from that study as in this one: that there is no alcoholic personality. From this conclusion Valliant leaped to the next incorrect conclusion, that there is no disease causing alcoholism as if a disease that causes alcohol addiction must be distinguishable from the psychological tests they were using. Not so. All three of these conclusions from the above studies are invalid and result in misleading concepts of causation of the future symptoms - anxiety attacks of one sort or another or future addictions. Because the symptoms studied in these works are predominant genetically based it makes no sense to attribute drugs as their cause even though NIDA wants this to be the case. As in most invalid association studies, the most likely way to connect the two attributes that are misconnected by the study in this article as one causing the other is by knowing that some other entity causes both of them instead, thus, the causal misassociation. In the current study, cigarettes are not the cause of the future anxiety, but rather, an underlying neurobiological etiology not uncovered in the prior psychological testing that causes both the smoking and the future anxiety disorders and thus smokers have a higher likelihood of also having anxiety disorders. This possibility was not taken into account in the study nor in its conclusions. It is exactly this underlying neurobiological entity that is being ignored by current researchers, for the most part, of addictions and other psychological symptomatology seen in drug addicts, including cigarette addicts. If accepted as is, this study has the potential to roll back the clock on real advances in addictions and to prevent the real paradigm of addictions from being realized. The researchers and the grant providers, NIDA, are both biased in favor of the conclusions of this study because it promotes their invalid addiction paradigm at the expense to addicts and society while simultaneously supporting the war on drugs and their other draconian treatments and policies. This study is a good example of misleading science used to promote damaging and ignorance-based public policy.
After reading Dr. Johnson's article in JAMA, we had this dialogue.
Him in black, me in red.
The dialogue begins:
Dr. Johnson: I am an addiction theorist. My addiction hypothesis is called Hypoism and is discussed in the book, Hypoic's Handbook - The Hypoism Paradigm of Addictions. I'm not for or against addictions including smoking. I am for a valid etiological addiction theory, though. I don't believe this currently exists. Be that as it may, I do believe that addictions do cause harm in addicts, but that scare tactics don't prevent addictions in hypoic-type people. In fact, scare tactics stigmatize and thereby hurt addicts in many ways. This is widely known from the long history of attempts to prevent addictions with compendiums of information about how bad addictions are for people. These tactics tend to imply that addicts are consciously self-destructive and stupid people, something that is just not true. Addicts get addicted knowing there are downsides to addictions. My opinion is that addictions occur unconsciously, however, and that conscious attempts to prevent addictions and other warnings don't keep hypoic-type addicts, the addicts with genetic neurobiological etiology, from getting addicted although they may well prevent non-hypoics from getting addicted to things like cigarettes. I do believe that the correct addiction paradigm will do more to prevent addictions and their complications than anti-addiction propaganda. Alcohol causes cirrhosis and smoking causes lung cancer, heroin causes... and cocaine causes... People still end up addicted despite knowing this. It may well be that smoking causes agoraphobia, generalized anxiety disorders, and panic attacks in some people, yet I doubt that it is the cause in all people with these symptoms. Thus, I am concerned with your study's overall validity and generalizability as well as whether it truly says what you "suggest" it's saying. To help me clarify this, could you please answer some questions I had about the study from JAMA? I read the article in JAMA and had some questions. 1) do the tests you used to determine childhood anxiety predict future agoraphobia, generalized anxiety disorders, and panic disorder? If so, could you please send me a copy of the paper showing that (I don't have access to a science library)? 2) If not, how do you know the subjects who developed these symptoms down the road wouldn't have anyway, irrespective of the previous anxiety testing results? 3) are you concluding that smoking causes these latter symptoms? If so, please tell me which part of the paper proves this and how it does? 4) how does this paper distinguish your conclusion, that smoking causes these latter symptoms, from a hypothesis that says that some underlying neurobiological entity causes both smoking and these latter symptoms in a subgroup of susceptible people in the context of the initial testing not being able to differentiate the two groups of people, those who smoke without getting latter symptoms and those who smoke and do get these symptoms? 5) is this just an association study, not proving causality and still be consistent with a subgroup whose underlying neurobiology leads to both smoking and the latter symptoms? Thanks for your help. dan umanoff, m.d.
From Dr. Johnson:
Dr. Umanoff:
Here are my answers in CAPS:
1) do the tests you used to determine childhood anxiety predict future agoraphobia, generalized anxiety disorders, and panic disorder? If so, could you please send me a copy of the paper showing that (I don't have access to a science library)?

I'M LEAVING FOR NEW ORLEANS IN AN HOUR AND WON'T BE ABLE TO RESPOND FOR THE NEXT TWO WEEKS. SEND ME YOUR ADDRESS AND I WILL MAIL YOU A COPY OF THE ARTICLE YOU REQUESTED. A NUMBER OF STUDIES, INCLUDING OUR OWN, HAVE INDICATED THAT CHILDHOOD ANXIETY MAY BE ASSOCIATED WITH INCREASED RISK FOR ANXIETY PROBLEMS DURING ADOLESCENCE OR EARLY ADULTHOOD. You didn't answer the question: do these childhood evaluations detect kids with the future triad of symptoms, yes or no? if not, then they are useless for this study. you need to find a method of evaluating kids who are likely to develop the symptom triad, then follow them for smoking or not, and latter development of the triad. These tests might have been predictive of both those who smoked and developed these anxiety symptoms later in early adulthood. One would need to find the ones predicted to smoke and develop anxiety symptoms, keep them from smoking and then see if they still develop anxiety symptoms or not, thus preventing the symptoms with non-smoking. Also, do the anxiety symptoms disappear with smoking cessation? Or, are the symptoms made worse with additional nicotine? Some experiments such as these would be necessary to confirm the conclusion, and in a double blind way. Before this result is validated, it must be repeated by other groups and some experimental variant must be used to distinguish the several causal possibilities.
2) If not, how do you know the subjects who developed these symptoms down the road wouldn't have anyway, irrespective of the previous anxiety testing results?
REGARDLESS OF WHETHER THEY HAD ANXIETY DISORDERS DURING ADOLESCENCE, THOSE WHO SMOKED 1 PACK/DAY CIGARETTES WERE AT INCREASED RISK FOR THE THREE ANXIETY DISORDERS DURING EARLY ADULTHOOD. Regardless? I think its important to identify those who develop these anxiety symptoms later to see whether it was this group that developed the symptoms irrespective (or concurrent) of smoking.
3)are you concluding that smoking causes these latter symptoms? If so, please tell me which part of the paper proves this and how it does?
OUR FINDINGS DO NOT PROVIDE DEFINITIVE PROOF THAT HEAVY SMOKING CAUSES ONSET OF ANXIETY DISORDERS. HOWEVER, OUR FINDINGS ARE CONSISTENT WITH THE HYPOTHESIS THAT HEAVY SMOKING DURING ADOLESCENCE MAY INCREASE RISK FOR ONSET OF ANXIETY DISORDERS. FIRST, WE FOUND THAT HEAVY SMOKERS WERE AT MARKEDLY INCREASED RISK FOR 3 ANXIETY DISORDERS AFTER CONTROLLING FOR ADOLESCENT ANXIETY, DEPRESSION, DRUG AND ALCOHOL USE, AGE, SEX, PARENTAL SMOKING, PARENTAL EDUCATION, AND PARENTAL PSYCHOPATHOLOGY. SECOND, WE FOUND THAT ANXIETY DISORDERS DURING ADOLESCENCE WERE NOT ASSOCIATED WITH INCREASED RISK FOR CIGARETTE SMOKING DURING EARLY ADULTHOOD.
4)how does this paper distinguish your conclusion, that smoking causes these latter symptoms, from a hypothesis that says that some underlying neurobiological entity causes both smoking and these latter symptoms in a subgroup of susceptible people in the context of the initial testing not being able to differentiate the two groups of people, those who smoke without getting latter symptoms and those who smoke and do get these symptoms?
FURTHER RESEARCH WILL BE NEEDED TO EXAMINE WHETHER THERE IS A COMMON NEUROBIOLOGICAL CAUSE FOR BOTH SMOKING AND ANXIETY DISORDERS. HOWEVER, OUR FINDINGS SUGGEST THAT THIS MAY BE UNLIKELY BECAUSE HEAVY SMOKING CLEARLY PRECEDED ONSET OF ANXIETY DISORDERS. IF THERE IS SUCH A COMMON CAUSE, THERE WOULD NEED TO BE AN EXPLANATION FOR THIS PARTICULAR SEQUENCE. IT IS POSSIBLE THAT SUCH AN EXPLANATION MAY BE FORTHCOMING, HOWEVER, SUCH AN EXPLANATION WOULD BE MUCH LESS PARSIMONIOUS THAN THE INTERPRETATION OF OUR FINDINGS THAT WE HAVE SET FORTH. IT MAY NOT ALWAYS BE IDEAL OR CORRECT TO ACCEPT THE MOST PARSIMONIOUS INTERPRETATION OF RESEARCH FINDINGS, BUT MY SCIENTIFIC TRAINING HAS TAUGHT ME TO STRIVE TO BE AS CONCISE AND PARSIMONIOUS AS PRACTICABLE.
5) is this just an association study, not proving causality and still be consistent with a subgroup whose underlying neurobiology leads to both smoking and the latter symptoms?
PLEASE SEE ANSWER TO #3 ABOVE.
Jeffrey G. Johnson, Ph.D.
Dan,
I wouldn't say "it's an association, not a causation," although it is perhaps true that only experimental research can demonstrate a cause-effect association in a convincing way. For example, does cigarette smoking cause lung cancer? Much of the research that has established this association has been non-experimental research like our study. It has often been stated that science does not prove anything, but only provides evidence in support of hypotheses. In this sense, I would certainly agree with you that we have not proven that heavy cigarette smoking causes the development of anxiety disorders.
So, what you're saying is that association studies are all equivalent and equal to "smoking causes lung cancer" associations? I dispute that. It may be difficult to design the experiment or series of experiments that would provide "proof" that smoking causes the anxiety triad, but that is the burden of the scientists who purport the association is causal. That is their job, and they shouldn't report the causal implication until they have done the "proof." I don't think I have to belabor this point.
Jeffrey Johnson
(continues on Letters to the NY Times page 12)









You can take the addiction out of the hypoic, but you can't take the Hypoism out of the addict.




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