Home Page of Hypoism, The Disease of Addictions

Web site advertising

The Overriding Principle

The reason for this web site


send me a message

Discussion Page

Buy the book

Buy the Book

Hypoism Issues

Role of Dopamine in Addiction Causation

Theory of Addiction - Hypoism Hypothesis

Why drug use is unconscious and against one's willfulness - not volitional

Misuse of the word choice in addictions



What Am I Angry About? - Don't Ask Me This Again

Disease Concept - A Perspective


Page Directory of this Site with Explanations and Links

The History of the Proof of Hypoism in the Wake of the P/R Paradigm page 1.

History page 2

Why Addiction Experts and Other People Are Ignoring Hypoism

Strange Brew


The Paradigm Vacuum in Addictions Today


What Does An Addiction Expert Know?

The Hypoism Addiction Hypothesis - An Evolutionary Psychology Perspective

Addiction Questionnaire

Misconceptions of addictions and addicts

What's Hypoism? What's an Addiction?


Why We Need Hypoism: A Comparison of the Principles and Consequences between the two Paradigms

Entitled to Your Opinion? Not Anymore.

HYPOICMAN: A non-recovering, unimpressed Hypoic

The Field of Addictionology: A Golfing Analogy


Contact Information

Hypoism Treatment Research

The Addiction Treatment Fraud Finally Exposed

Hypoism Treatment Research Proposal



The National Association for the Advancement and Advocacy of Addicts

Make A Contribution To The N4A

Addict Discrimination Documentation

Social Innovations Award 2000 for The N4A

Third Millennium N4A Conference Keynote Address on Hypoism - Pathophysiology in Addictions vs. Superstition

N4A Goes on the Offensive - Suggesting Real Action

The Verdict

Blind Faith?

Learn More About the Book

Letters from book readers

Title Page of Book

Book Blurb

Book Cover

Back Cover

Table of Contents



Opening Statement

Chapter 1

Vision For The Future

Outcomes of Hypoic's Handbook


Book Corrections

Harm reduction prototype: Swiss PROVE program

Book Reviews

The Phoenix Magazine

Hypoics Not-Anonymous

Hypoics Not-Anonymous

Things You Can Do

What you can do---

My Kids

Special Links

Special Links to important web sites

Addiction Links on the Web

Addiction Genetics

Recent Genetic Studies on Various Addictions from a Large Twin Registry

Genetic Studies page 2.

Gateway theory finally disproven

Celera Discovers Millions of Tiny Genetic Differences in People

Interesting Addiction Science

Clinically Important Neurotransmitter Deficiencies

Hypoism Magazine-Articles by and for Hypoics


#1 Hatred, #2 The Words: Opinion, Belief, and Knowledge, #3 Hate Addiction

#4 The Drug War War, #5 Evolution vs. Creationism Revisited for Addictions

#6 American Society for Addiction Medicine Statement for Recovering Physicians

#7 Issues Peculiar to the Disease of Addictions

#8 Critique of Alan Lechner's (NIH), "The Hijacked Brain Hypothesis."

#8a. Update!! Dr. Leshner recently makes a change

#9 MY STORY - The Doctor Drug War - Wrong and Wasteful p.1, 1/6/00

The Doctor Drug War p.2

Doctor Drug War p.3

Doctor Drug War p.4

Doctor Drug War p.5

Affidavit for judicial review of NYS Dept. of Ed.

#10 The Superstition Instinct 3/1/00

#11-Conflict of Interest in Addiction Research

#12 - Controlled Drinking Lands On Its Ass

#13 - The Kennedy Curse or Kennedy Hypoism?

#14 - The Lord's Prayer for Hypoics

#15 - Replacing Alan Leshner is the only way to end the Drug War

#16 - The Brain Addiction Mechanism and the COGA Study

#17 - Letter to the director of the National Academy of Medicine's Board on Neurobiology and Behavior Health on Addictions

#18 - Is Addiction Voluntary, A Choice, as Leshner and NIDA Insist?

#19 - Bush's Alcoholism and Lies

#20 - A P/R Paradigm Addict - "Cured?"

#21 - Congress Misled and Lied to by NIAAA

#22 - Special Letter to the Times on Addiction Genetics

#23 - JAMA Editor Publishes According to His Beliefs, Not Science

#24 - Smoking as Gateway Drug. I Don't Think So!


#25 - One Less Heroin Addict. But At What Cost?

#26 - An Open Letter to the Judge who Sentences Robert Downey, Jr.

#27 - Letter To Schools About The Pride Program Against Drugs

#28 - A Letter To Bill Moyers, Close To Home, and PBS


#30 - Brookhaven Labs Provide More Evidence For Hypoism

#31 - Addiction Prevention Revisited


#33 - NIDA Is Close But No Cigar

#34 - Bush's Addict Discrimination and Hypocricy Begins

#35 - Maya Angelou's, "Still I Rise."

#36 - Leshner Lies To Congress

#37 - Addiction Combos

#38 Brain tumor proves Hypoism hypothesis

#39: So-called Availability Debunked as Contributor of Addictions

#40 - Hypoism Reproduced By A Pill



The Hypoism Blog - The Addiction Blog

The Addiction Blog 4/17/11 -

The Addiction Blog 9/14/10 - 4/16/11

The Addiction Blog 11/12/09 - 9/14/10

The Addiction Blog 7/23/09 - 11/09/09

The Addiction Blog 5/16/09 - 7/22/09

The Addiction Blog 3/3/09 - 5/13/09

The Addiction Blog 8/3/08 - 3/3/09

The Addiction Blog 4/1/07 - 8/3/08

old letters

My NY Times Letters to the Editor page 1.

My NY Times Letters to the Editor page 2.

My NY Times Letters to the Editor page 3.

My NY Times Letters to the Editor page 4.

My NY Times Letters to the Editor page 5.

My New York Times Letters to the Editor page 6.

My Letters to the editor of the NY Times page 7.

My Letters to the Editor of the NY Times page 8.

NY Times Letters Page 9.

New York Times Letters Page 10

My NYT Letters page 11

NY Times Letters page 12.

NY Times letters p. 13

Letters to the NY Times page 14.

Letters to Newsday

Letters To The Los Angeles Times

Creationism/Evolution Letter to BAM 11-25-05


Committee for Physician Health Speech

The Future of Addictions

Addict Discrimination in the News

Mandated Treatment for Welfare Recipients

Anorectic Murdered by Doctors out of Ignorance and "Desperation"(10/20/99)

Six Dead Heroin Addicts-Enough? 10/31/99

American Society of Addiction Medicine Discrimination

Darryl Strawberry Punished Again

South Carolina Forces Pregnant Women to Take Drug Tests

When it comes to drugs, the constitution doesn't apply

Parents of Overweight Girl Will Sue New Mexico



Download Files

huffington post

Custom HTML


Hypoics are born, not made.

Dan F. Umanoff, M.D.  
8779 Misty Creek Dr.  
Sarasota, Florida 34241  





ronbeas: I see you're an engineer. You should have less trouble with Hypoism than most. The part of the brain that causes addictions is quite similar to an oil burner thermostat set so high by inherited low (hypo) activity genetic alleles that it, as the on-off switch for the decision-making apparatus, is always ON. The more severe the Hypoism the, higher the setting; the more ON it is. [Outside influences, so-called environmental influences, such as “stress,” can affect (raise) the settings, but there’s no evidence that stress alone, absent the inherited genetic deficiencies, can cause addictions. In other words, stress can exacerbate Hypoism but not cause addictions absence pre-existing Hypoism.] The second critical issue is the location of this "thermostat" in the brain. Read the book, The Emotional Brain, by Joseph LeDoux, who spent his life studying the amygdala and other parts of the Limbic system, the area of the brain where this "thermostat" is located (the unconscious and instinctive brain). The key properties of this part of the brain are 1) it has many axons going to the cortex (conscious brain) but few axons going to it from the cortex. 2) It unconsciously effects decisions while being unamenable to conscious influences. This means that the homeowner is unable to change the settings of the thermostat. Because this thermostat directs three processes, behavior motivation, decision-making, and evaluation of situations (internal and external), this combination leads to three consequences in people who have critically low activity of the "thermostat." 1) Constant and unconscious motivation to raise the activity of the deficient neurotransmitters in the thermostat by using chemicals or behaviors or beliefs that raise these levels, drugs, and instinctive behaviors and beliefs (drug and behavioral addictions). 2) Decision mistakes that raise these levels (unrelated to realistic and consciously known consequences), and 3) Evaluation mistakes concerning self (low self esteem) and situations that also lead to disasters. Thus, this part of the brain which is so valuable in instinctive decision-making in non-hypoics becomes a liability in hypoics when used to make everyday survival decisions and evaluations. And, it is unresponsive to cortical inputs that might have some ameliorating influence on it (psychotherapy, just-say-no, fear of consequences, etc.) Thus, hypoics appear from the outside and even to themselves to get addicted and make seemingly self-destructive decisions while ignoring reality. However, because of the engineering of this system, these are against the conscious "will" of the hypoic and thus appear compulsive and impulsive. The characteristics of this system that were so beneficial to human survival hundreds of thousands of years ago, when commodities were scarce, are today, on the other hand, in the presence of limitless commodities, a liability (the evolutionary psychology of this system and its genetic variants-hypoic genes).

Add to the above thermostat principles one further major hooker: Every time the oil burner is turned on, used to heat the house, this itself causes a resetting of the thermostat to an even higher level and, moreover, opens the windows of the house to the cold air outside! [This is called down-regulation] The more the burner is used, the higher becomes the setting and the more open become the windows. In neurobiological terms all this is called neurophysiological adaptation. This adaptive response by the living brain is what makes the brain so much more confounding than a simple mechanical thermostat. This is why addicts need more and more drugs to get the same effect (tolerance) as well as withdrawal symptoms. Lastly, these new high setting remain higher than when they were to begin with for years afterwards, the reason for craving and relapses even following detox and recovery. [The current theory of addiction, The Hijacked Brain Hypothesis, utilizes the information in this paragraph but not that from the first paragraph by saying the addict-to-be uses drugs and behaviors initially for conscious and willful reasons but then neurophysiological adaptation occurs and this causes the addiction. This theory is false because the concepts in both paragraphs have been proven to be required for addiction to happen.]

Lastly, this entire system (both the above paragraphs are required for addiction and have been proven to be the case) is on automatic and is outside the control of the owner of the thermostat.

Because psychologists have never understood or appreciated the workings of this neurobiological system, they have misconstrued decisions and behaviors coming from it and devised "therapies" that are based on these misunderstandings that, by their very incorrect nature, don't work to help people with Hypoism. My book delineates this conceptual history and the workings of this complex mechanism in the production of Hypoism along with its implications for "recovery" from this disease (rather than from its symptoms, addictions) as well as public policy changes demanded by this knowledge. Hypoism is an inconceivable paradigm until one dumps all preconceived and incorrect beliefs about how this part of the brain actually works. This is difficult to do, but is necessary to move onto a valid understanding of addictions, symptoms of HYPOfunctioning (thus the derivation of the name of the disease, HYPOism) of the regulator of the decision-making apparatus. Hypoism is the first delineated genetic disease of this part of the brain and is the beginning of the full understanding of how this part of the brain actually works. Hypoism turns addictionology on its head and presents the world, for the first time, with a human nature paradigm that will lead to a better understanding of how the human brain works, via its neurobiological and evolutionary underpinnings rather than by psychobabble. If you can dig this, the book will be quite helpful to you. There's tons of valid human and animal research behind this hypothesis that is in the midst of being delineated and proved while we sit here although the researchers who are proving it haven't yet put the hypothesis together in such a parsimonious package as I have in Hypoism.

You can take the addiction out of the hypoic, but you can't take the Hypoism out of the addict.

Sign In